Constantinos Chrysostomou, MD

Director, Congenital Cardiac Intensive Care

Constantinos Chrysostomou, MD, is Director of Congenital Cardiac Intensive Care at Cedars-Sinai’s Department of Pediatrics, Division of Pediatric Cardiology, Congenital Heart Program and Heart Institute. He is board certified in pediatric cardiology and certified in pediatric cardiac critical care.

Dr. Chrysostomou is a pioneer in the field of pediatric cardiac ICU. He is the first to have studied and implement the routine use of dexmedetomidine, a safer sedative agent for critically ill neonates and children with cardiac disease. In addition to his long standing commitment in the development of safer sedation protocols that can lead to improved neurodevelopmental outcomes, he is also responsible for the discovery of dexmedetomidine’s anti-arrhythmic properties. His work on dexmedetomidine for the treatment and prevention of ventricular and supraventricular tachyarrhythmias is nationally recognized and was published in several high impact pediatric journals. This work has been referred to as breakthrough research from which other projects have since been undertaken to investigate dexmedetomidine’s anti-arrhythmic properties. Furthermore, Dr. Chrysostomou’s research expands into the field of mechanical circulatory support. In a recent publication in the Journal of Thoracic and Cardiovascular Surgery, Dr. Chrysostomou demonstrated that a significantly improved survival after cardiac ECMO is feasible (75% vs. national average of 45%). Dr. Chrysostomou has served as a principal investigator for several multicenter studies.

In addition to numerous scientific articles and abstracts, Dr. Chrysostomou has written book chapters and is both a reviewer for several journals and the associate editor for Frontiers in Pediatric Cardiology. A prolific speaker, he has presented and lectured on his area of expertise at both the national and international level.

Dr. Chrysostomou earned his medical degree from the University Medical School of Debrecen in Hungary. He completed his residency in pediatrics at the University of Minnesota, pediatric cardiology fellowship at the University of Miami and a fellowship in pediatric cardiac ICU at Children’s Hospital of Pittsburgh.

Dr. Chrysostomou is a member of several professional organizations including the American Academy of Pediatrics, Society of Critical care Medicine, Pediatric Cardiac Intensive Care Society and is a founding member of the World Society of Pediatric and Congenital Heart Surgery.

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