Sebastien Fuchs, MD, PhD

Assistant Professor of Pathology
Research Scientist II
Biomedical Sciences and Experimental Pathology

Email:  Sebastien.Fuchs@cshs.org
Phone:  310-423-7768

Education and Training

  • University Broussais-Hôtel-Dieu, Paris, France; MD
  • University Paris VII / College de France, Paris, France: PhD
  • Postdoctoral Fellow, Department of Pathology, Emory University,Atlanta, GA

Research Interests

  • Angiotensin independent biochemistry and physiology of angiotensin-converting enzyme.
  • Fibrotic processes with emphasis on pulmonary fibrosis
  • Properties of the tetrapeptide AcSDKP
  • Alzheimer’s disease, amyloid-β biochemistry

Awards and Activities

  • Recipient, CART Fund for Alzheimer Research Award
  • Recipient, NIH/ NHLBI Pathway to Independence Award
  • Recipient, Beginning Grant in Aid from the American Heart Association
  • Recipient, research fellowship from the National Kidney Foundation
  • Recipient, Grant fellowship from Academie Nationale de medecine
  • Academic Editor for PlosONE

Selected Publications

  • Ong FS., Lin CX., Campbell DJ., Okwan-Duodu D., Chen X., Blackwell WLB., Shah KH., Gonzalez-Villalobos RA., Shen, XZ. and Fuchs S., Bernstein KE.  Increased angiotensin II induced  hypertension and inflammatory cytokines in mice lacking angiotensin converting enzyme N-domain activity. Hypertens. 2012;59:283-90.
  • Shen XZ, Ong FS, Bernstein EA, Janjulia T, Blackwell WL, Shah KH, Taylor BL, Gonzalez-Villalobos RA, Fuchs S, Bernstein KE. Nontraditional roles of angiotensin-converting enzyme. Hypertens 2012;59:763-8.
  • Gonzalez-Villalobos RA, Billet S, Kim C, Satou R, Fuchs S, Bernstein KE, and Navar LG.  Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion.  J Am Soc Nephrol. 2011;22:449-59.
  • Bernstein KE, Shen XZ, Gonzalez-Villalobos RA, Billet S, Okwan-Duodu D, Ong FS, and Fuchs S.  Different in vivo functions of the two catalytic domains of angiotensin converting enzyme (ACE).   Curr Opin Pharmacol. 2011;11:105-11.
  • Lin C, Datta V, Okwan-Duodu D, Chen X, Fuchs S, Alsabeh R, Billet S, Bernstein KE, and Shen XZ.  Angiotensin-converting enzyme is required for normal myelopoiesis. FASEB J. 2011;25:1145-55.

Click here for a list of peer-reviewed publications by Sebastian Fuchs, MD, PhD

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