Case of the Month: October, 2010 Page 2

Answer: 1) Multiple asymmetric white matter lesions with FLAIR hyperintensity and peripheral enhancement. No restricted diffusion.

[The remainder of the choices are descriptions of the following entities: 2) Multiple sclerosis , 3) Fabry’s Disease, 4) autoimmune mediated vasculitis.]

Question: Differential diagnosis for mutlifocoal white matter/basal ganglia lesions considering clinical factors such as immunosuppression, recent infection, or recent vaccination:

1. Acute disseminated encephalomyelitis (ADEM)
2. Multiple Sclerosis (MS)
3. Auto-immune mediated vasculitis
4. Fabry’s Disease
5. Bechet’s