Key Publications on Heart Transplants

Following are key publications from the Cedars-Sinai Heart Transplant Program’s leadership and faculty:

1. Kobashigawa JA, Katznelson S, Laks H, Johnson JA, Yeatman L, Wang XM, Chia D, Terasaki PI, Sabad A, Cogert GA, Trosian K, Hamilton MA, Moriguchi JD, Kawata N, Hage A, Drinkwater DC, Stevenson LW. Effect of pravastatin on outcomes after cardiac transplantation. N Engl J Med 1995;333:621-7.

2. Kobashigawa JA, Leaf DA, Lee N, Gleeson M, Liu H, Hamilton MA, Moriguchi JD, Kawata N, Einhorn K, Herlihy E, Laks H.  A controlled trial of exercise rehabilitation after heart transplantation.  N Engl J Med 1999 Jan;340:272-7.

3. Eisen HJ, Tuzcu EM, Dorent R, Kobashigawa JA, Mancici D, Valentine-von Kaeppler HA, Starling RC, Sorensen K, Hummel M, Lind JM, Abeywickrama KH, Bernhardt, P.  Everolimus for the Prevention of Allograft Rejection and Vasculopathy in Cardiac Transplant Recipients.  N Engl J Med 2003; 349:847-58.

4. Kobashigawa JA, Moriguchi JD, Laks H, Wener L, Hage A, Hamilton MA, Cogert G, Marguez A, Vassilakis ME, Patel J, Yeatman L.  Ten-Year Follow-up of a Randomized Trial of Pravastatin in Heart Transplant Patients. J Heart Lung Transplant 2005. Nov;24(11):1736-1740

5. Kobashigawa JA, Tobis JM, Starling RC, Tuzcu EM, Smith AL, Valantine HA, Yeung AC, Mehra MR, Anzai H, Oeser BT, Abeywickrama KH, Murphy J, Cretin N.  Multicenter Intravascular Ultrasound (IVUS) Validation Study Among Heart Transplant Recipients: Outcomes After 5 Years. J Am College of Cardiology 2005;45(9):1532-1537.

6. Kobashigawa JA, Patel J, Furukawa H, Moriguchi JD, Yeatman L, Takemoto S, Marquez A, Shaw J, Oeser BT, Subherwal S, Wu GW, Kawano J, Laks H. Five-Year Results of a Randomized Single Center Study of Tacrolimus Versus Micoremulsion Cyclosporine in Heart Transplant Patients. J Heart and Lung Transplant  2006;25(4):434-9.

7. Kobashigawa JA, Tobis JM, Mentzer RM, Valantine HA, Bourge RC, Mehra R, Smart FW, Miller LW, Tanaka K, Haiyan L, Gjertson DW, and Gordon RD.  Mycophenolate mofetil reduces intimal thickness by intravascular ultrasound after heart transplantaion: reanalysis of the multicenter trial.  Am J Transplant 2006;6(5 Pt 1):993-7.

8. Kobashigawa JA, Miller LW, Russell SD, Ewald GA, Zucker M, Goldberg LR, Eisen HJ, Salm K, Tolzman D, Gao J, Fitzsimmons WE, First R.. Tacrolimus with Mycophenolate Mofetil (MMF) or Sirolimus vs. Cyclosporine with MMF in Cardiac Transplant Patients: 1-Year Report. Am J Transplant 2006;6(6):1377-86.

9. Kobashigawa, JA. Cardiac Allograft Vasculopathy in Heart Transplant Patients: Pathologic and Clinical Aspects for Angioplasty/Stenting. Editorial Comment. J Am Coll Cardiol 2006;48(3):462-3.

10. Kobashigawa JA, Renlund DG, Gerosa G, Almenar, Eisen HJ, Keogh AM, Lehmkuhl HB, Livi U, Ross H, Segovia J, Yonan, Novartis Reps. A 12 month, single blind, randomized, parallel group, multicenter study, to investigate the efficacy and safety of enteric coated mycophenolate sodium (EC-MPS) compared with mycophenolate mofetil (MMF) in de novo heart recipients: 12 month results. J Heart Lung Transplant 2006; 25(8):935-41.

11. Kobashigawa JA, Starling R, Mehra M, Kormos R, Bhat G, Barr M.  Multi-center Retrospective Analysis of Cardiovascular Risk Factors Affecting Outcome of De Novo Cardiac Transplant Recipients.  J Heart Lung Transplant. 2006;25(9):1063-9.

12. Kobashigawa JA, Patel J. Review:  Immunosuppression for heart transplantation: where are we now? Nat Clin Pract Cardiovasc Med. 2006;3(4):203-12.

13. Kobashigawa JA. Contemporary Concepts in Noncellular Rejection. Heart Failure Clin 2007;3(1):11-15.

14. Flechner SM, Kobashigawa J, Klintmalm G.  Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity. Clin Transplant 2008;22:1-15.

15. Kobashigawa J, Mehra M, West L, Kerman K, George J, Rose M, Zeevi A, Reinsmoen N, Patel J, Reed E, Consensus Conference Participants. Report from a Consensus Conference on the Sensitized Patient Awaiting Heart Transplantation. J Heart Lung Transplant 2009 Mar;28(3):213-25.

16. Mehra MR, Crespo-Leiro MG, Dipchand A, Ensminger SM, Hiemann NE, Kobashigawa JA, Madsen J, Parameshwar J, Starling RC, Uber PA.  International Society for Heart and Lung Transplant working formulation of a standardized nomenclature for cardiac allograft vasculopathy—2010. J Heart and Lung Transplant. 2010 June;29(6): 717-27.

17. Costanzo MR, Dipchand A, Starling R, Anderson A, Chan M, Desai S, Fedson S, Fisher P, Gonzales-Stawinski G, Martinelli L, McGiffin D, Smith J, Taylor D, Meiser B, Webber S, Baran D, Carboni M, Dengler T, Feldman D, Frigerio M, Kfoury AG, Kim D, Kobashigawa J, Shullo M, Stehlik J, Teuteberg J, Uber P, Zuckermann A, Hunt S, Burch M, Bhat G, Canter C, Chinnock R, Crespo-Leiro M, Delgado R, Dobbels F, Grady K, Kao W, Lamour J, Parry G, Patel JA, Pini D, Towbin J, Wolfel G, Delgado D, Eisen H, Goldberg L, Hosenpud J, Johnson M, Keogh A, Lewis C, O'Connell J, Rogers J, Ross H, Russell S, Vanhaecke J.  The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Heart and Lung Transplant August 2010 ; 29 (8): 914-956.

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