Women's Health Clinical Trials

Cedars-Sinai Heart Institute is currently conducting the following women's health clinical trials:

Coronary Microvascular Disease and Endothelial Function in Women

Principal Investigator: C. Noel Bairey Merz MD

IRB Approval Number: 8221

Contact:  Puja Mehta, MD (310) 423-9680

Status: Enrolling

Summary: This study aims to specifically study a group of female patients who have chest pain or other signs or symptoms suggestive of heart disease but don’t have visible blockages in the large heart arteries. Women with chest pain who undergo heart catheterization but have no blockages of large heart arteries will be consented and enrolled. They will be asked to fill out questionnaires about their medical history and undergo testing during heart catheterization that would test for abnormalities in their small heart arteries using acetylcholine and adenosine infusions. In addition they will be asked to undergo a non-invasive test called Peripheral Arterial Tonometry or PAT and in some cases, if indicated a Cardiac Magnetic Resonance (CMR) imaging test.


Cardiac Magnetic Resonance Imaging Normal Reference Control Group Testing – Ancillary Study to Coronary Endothelial Function and Microvascular Disease in Women

Principal Investigator: C. Noel Bairey Merz, MD

IRB Approval Number: 11753

Contact:  Rosario Ando (310) 423-9666

Status: Enrolling

Summary: The purpose of this research is to understand how to apply cardiac magnetic resonance imaging (CMR) to women with small artery heart disease by looking at the CMRs of women without heart disease. In order to achieve this goal, 20 women between the ages 35-65 years with no known heart disease or heart disease risk factors will be recruited.

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