Innovations and Discoveries


The Cedars-Sinai Heart Institute is known around the world for its commitment to translating leading-edge research into routine patient care.  Through the years, our innovations and discoveries have improved the prognosis and quality of life for patients battling heart disease. 
  1924 First electrocardiogram machine installed
 in Los Angeles.
 1952  First use of the thrombolytic enzymes to
 dissolve blood clots in the heart.
 1959  First description of the syndrome of
 vasopastic angina. 
 1970  Invention of the Swan-Ganz catheter to
 measure blood flow and heart pressures.
 1973  First use of drugs to dilate blood vessels
 in heart failure patients, revolutionizing
 the way severe heart disease is treated.
 1981  First use of radioactive isotope Tc-99m
 to assess blood flow throughout the
 heart.
 1994 First us of the mutant gene-based therapy
 (apo A-1 Milano) to fight atherosclerosis
 in experimental animals- a step toward
 new treatments for coronary artery
 disease.
 1995  Developed imaging software used worldwide
 for noninvasive quantification of heart
 function.
 2001 First medical center in California and
 one of the first in the nation to use a
 portable artificial heart.
  2005  First enrolling center in a national
 trial of percutaneous mitral valve repair.
 2006  First comprehensive women's heart center in
 the United States encompassing clinical care,
 research and education
 2009  First clinical trial of cardiac-derived stem cells
 to treat heart attack patients
 2010  National leader in clinical trials of new
 catheter procedure to replace aortic valves
 nonsurgically
 2010  First hospital unit in California dedicated
 solely to treating advanced heart failure patients 
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