Innovations and Discoveries

2014 Heart Institute Annual Report

Cedars-Sinai's international reputation for outstanding heart care is built on decades of innovation and leading-edge research, including:

  • Eduardo Marbán, MD, PhD and the Cedars-Sinai Heart Institute completed enrollment in the world’s first autologous cardiac stem cell clinical trial, caduceus, with results forthcoming in less than a year. In the meantime, our work produced some surprises-such as the finding that high doses of antioxidant nutritional supplements may increase genetic abnormalities in stem cells and thereby predispose supplement takers to developing cancer.
  • Our interventional cardiology team, led by Raj Makkar, MD and Saibal Kar, MD, continued to pioneer the development of percutaneous heart valve repair and re-placement. Cedars-Sinai Heart Institute physicians have performed more percutaneous mitral valve repairs and aortic valve replacements than any other U.S. medical center. Our physicians will play a primary role in teaching these techniquesto fellow practitioners around the world, and in directing the next wave of clinical studies.
  • In electrophysiology, Sumeet Chugh, MD, director of the landmark Oregon Sudden Unexpected Death Study, made significant progress in the quest to predict which individuals are most likely to suffer sudden cardiac arrest.
  • Our 30-bed Advanced Heart Failure Unit began admission of congestive heart failure and heart transplant patients. The first of its kind in California, the unit seeks to improve upon the standard of care with a team approach to patient management, real-time monitoring of heart function and intensive heart-health education.
  • Our hypertension team headed by Ronald Victor, MD, subjected a blood pressure screening program to scientific scrutiny. In an important public health finding, Victor’s study demonstrated that blood pressure programs based in African-American barbershops are effective in helping participants control blood pressure and prevent hypertension-related complications.

From cardiac rehabilitative and preventive care and heart transplantation to the training of the heart specialists of tomorrow and leading-edge research that is deepening medical knowledge and practice, Cedars-Sinai Heart Institute is known around the world for excellence.

The Barbra Streisand Women's Heart Center provides risk assessment, diagnosis and heart disease care that is specifically tailored to women.