Daniel J. Wallace, MDAssociate Director, Fellowship Program, Rheumatology |
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Awards and Activities
| Healthcare Professional Leadership Award, Sjogren's Syndrome Foundation | 2012 |
| Medical Achievement Award, SLE Foundation | 2011 |
| Editor: The Sjogrens Book (Sjogrens Syndrome Foundation) 4th and 5th edition | 2007 - 2012 |
| Author: The Lupus Book | Current |
| Editor: Dubois Lupus Erythematosus 3rd-8th editions | 1985 - 2012 |
| President, Research and Education Foundation of the American College of Rheumatology | 1994 - 2000 |
| President, Lupus Foundation of America | 1999 - 2000 |
| Founder and chairman of Scientific Advisory Board: Lupus LA | 2000 |
| Medical Advisory Board: Lupus Research Institute | 2012 |
Research Focus
Systemic lupus erythematosus: genetic susceptibility, environmental risk, biomarkers, clinical trials, patient reported outcome measures, cardiac complilcations
Rheumatoid arthritis: environmental risk, clinical trials
Sjogren's syndrome: biomarkers, genetics, clinical trials
Research Contributions
Leader in the discovery of new autoantibodies, clinical trial design for autoimmune diseases, and has published significant insights into the mechanisms of actions of drugs used for these disorders and their environmental and genetic associations.
Current investigations include:
Collaborative efforts with several lupus and Sjogren's consortiums (e.g., SLICC) to evaluate biomarkers, genetic and environmental associations, outcomes and prognostic markers, disease activity indices. Involved in 40 different initiatives including 10 biologic agents in clinical trials. Recent grant to evaluate clinical optimization of autoantibody testing. Collaboration with Continuing Medical Education for quality improvement in lupus education.
Selected Publications
- Klinenberg JR, Wallace D: Plasmapheresis in Raynaud's disease. Lancet, 1(8077): 1310-1, 1978
- Wallace DJ, Podell T, Weiner J, Klinenberg JR, Forouzesh S, Dubois EL: Systemic lupus erythematosus--survival patterns. Experience with 609 patients. JAMA, 245(9): 934-8, 1981
- Wallace D, Goldfinger D, Lowe C, Nichols S, Weiner J, Brachman M, Klinenberg JR: A double-blind, controlled study of lymphoplasmapheresis versus sham apheresis in rheumatoid arthritis. N. Engl. J. Med., 306(23): 1406-10, 1982
- Wallace DJ, Margolin K, Waller P: Fibromyalgia and interleukin-2 therapy for malignancy. Ann. Intern. Med., 108(6): 909, 1988
- Wallace DJ: The use of quinacrine (Atabrine) in rheumatic diseases: a reexamination. Semin. Arthritis Rheum., 18(4): 282-96, 1989
- Chong PJ, Matzner WL, Wallace DJ, Klinenberg JR, Toyoda M, Jordan SC: 1,25 dihydroxyvitamin-D3 regulation of immunoglobulin production in peripheral blood mononuclear cells of patients with systemic lupus erythematosus. J. Autoimmun., 2(6): 861-7, 1989