Bernstein Lab
Kenneth E. Bernstein, MD, joined Cedars-Sinai as the director of the Experimental Pathology Division in 2008. His laboratory has made several important discoveries concerning the role of angiotensin-converting enzyme (ACE) in blood pressure control, renal function, immune response, reproduction, and hematopoiesis. He recently published an article about the biological functions of ACE in Pharmacological Reviews. Bernstein is the co-recipient of the 2005 Novartis Excellence Award for Hypertension Research and the recipient of the 2007 Basic Research Prize from the American Heart Association.
The Bernstein Laboratory is affiliated with the Department of Pathology and Laboratory Medicine and the Department of Biomedical Sciences.
- Angiotensin Converting Enzyme (ACE)
- Hypertension
- Role of ACE in the Immune Response
- Alzheimer's Disease
- MHC Class I Peptide Processing
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Bernstein Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Angiotensin converting enzyme (ACE) activity enhances bactericidal immunity of neutrophils.
Khan Z, Shen XZ, Bernstein EA, Giani JF, Eriguchi M, Zhao T, Gonzalez-Villalobos RA, Fuchs S, Liu GY, Bernstein KE.
Blood, 2017 Jul 20;130(3):328-339. PMID: 28515091. PMCID: PMC5520468
Angiotensin converting enzyme (ACE) enhances the response of myeloid cells in innate and adaptive immunity.
Bernstein KE, Khan Z, Giani JF, Cao D-Y, Bernstein EA, Shen XZ.
Nature Reviews Nephrology, 2018 May;14(5):325-336. PMID:29578208 PMCID: PMC6192041
The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease.
Eriguchi M, Bernstein EA, Veiras L, Khan Z, Cao D-Y, Fuchs S, McDonough AA, Gonzalez-Villalobos RA, Bernstein KE, Giani JF.
J Am Soc Nephrol. 2018 Oct;29(10):2546-256. PMID:30185469 PMCID: PMC6171283
Contact the Bernstein Lab
8700 Beverly Blvd.
Davis Building, Room 2018
Los Angeles, CA 90048