Pharoah Lab
Prior to arriving at Cedars-Sinai, Dr. Pharoah led a research group for 20 years at the University of Cambridge studying the inherited genetics of hormone-related cancers, the molecular pathology of breast and ovarian cancer and the association between the molecular tumor characteristics and clinical outcomes.
Personal Statement
I am a physician-scientist that has led a research group at the forefront of international efforts to unravel the inherited basis of susceptibility to ovarian and breast cancer, from the early candidate-gene association studies to the most recent application of next-generation sequencing. My contributions have been recognized, most notably by the international John Graunt Prize for Extraordinary Achievement in Population Sciences in 2016. I have also taken a prominent role in the translation of the research into clinical and public health practice, creating the PREDICT breast and PREDICT prostate tools for cancer prognosis that are used worldwide."
Paul Pharoah
Breakthrough Research Areas
Over the past decade my group has been instrumental in unraveling the genetic architecture of epithelial ovarian cancer. We have led international efforts to characterize the role of common gemline genetic variation as well as rare, loss-of-function variation in the protein coding region of the genome. We have developed the PREDICT breast and PREDICT prostate tools that predict prognosis and treatment benefits. The PREDICT websites have been accessed over 2 million times.
Collaborations
Internal
- Gayther Laboratory
- Jones Laboratory
- Samuel Oschin Comprehensive Cancer Institute
Publications
Learn more about the recent research publications from the Pharoah Lab.
Contact the Pharoah Lab
700 N. San Vicente Blvd.,
West Hollywood, CA 90069