Publications
See a complete PubMed list of publications by Timothy R. Crother, PhD.
Selected Key Publications
- Dagvadorj J, Mikulska-Ruminska K, Tumurkhuu G, Ratsimandresy RA, Carriere J, Andres AM, Marek-Iannucci S, Song Y, Chen S, Lane M, Dorfleutner A, Gottlieb RA, Stehlik C, Cassel S, Sutterwala FS, Bahar I, Crother TR, Arditi M. Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2015632118.
- Chen S, Crother TR. MD-2 as a possible therapeutic target for atherosclerosis. EBioMedicine. 2020 May;55:102760.
- Chen S, Markman JL, Shimada K, Crother TR, Lane M, Abolhesn A, Shah PK, Arditi M. Sex-specific effects of the Nlrp3 inflammasome on atherogenesis in LDL receptor-deficient mice. JACC Basic Transl Sci. 2020 Jun;5(6):582-598.
- Markman JL, Porritt RA, Wakita D, Lane ME, Martinon D, Rivas MN, Luu M, Posadas EM, Crother TR, Arditi M. Loss of testosterone impairs anti-tumor neutrophil function. Nat Commun. 2020 Mar 31;11(1):1613.
- Crother TR, Porritt RA, Dagvadorj J, Tumurkhuu G, Slepenkin AV, Peterson EM, Chen S, Shimada K, Arditi M. Autophagy limits inflammasome during chlamydia pneumoniae infection. Front Immunol. 2019 Apr 12;10:75.
- Noval Rivas M, Wakita D, Franklin MK, Carvalho TT, Abolhesn A, Gomez AC, Fishbein MC, Chen S, Lehman TJ, Sato K, Shibuya A, Fasano A, Kiyono H, Abe M, Tatsumoto N, Yamashita M, Crother TR, et al. Intestinal permeability and IgA provoke immune vasculitis linked to cardiovascular inflammation. Immunity. 2019 Sep 17;51(3):508-521.e6.
- Shimada K, Porritt RA, Markman JL, O’Rourke JG, Wakita D, Rivas MN, Ogawa C, Kozhaya L, Martins GA, Unutmaz D, Baloh RH, Crother TR, et al. T-cell-intrinsic receptor interacting protein 2 regulates pathogenic T helper 17 cell differentiation. Immunity. 2018 Nov 20;49(5):873-885.e7.
- Porritt RA, Crother TR. Chlamydia pneumoniae infection and inflammatory diseases. For Immunopathol Dis Therap. 2016;7(3–4):237–254.
- Rivas MN, Crother TR, Arditi M. The microbiome in asthma. Curr Opin Pediatr. 2016 Dec;28(6):764–771.
- Wheeler ML, Limon JJ, Bar AS, Leal CA, Gargus M, Tang J, Brown J, Funari VA, Wang HL, Crother TR, et al. Immunological consequences of intestinal fungal dysbiosis. Cell Host Microbe. 2016 Jun 8;19(6):865–873.
- Chiba N, Shimada K, Chen S, Jones HD, Alsabeh R, Slepenkin AV, Peterson E, Crother TR, Arditi M. Mast cells play an important role in Chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway. J immunol. 2015 Apr 15;194(8):3840–3851.
- Jupelli M, Shimada K, Chiba N, Slepenkin A, Alsabeh R, Jones HD, Peterson E, Chen S, Arditi M, Crother TR. Chlamydia pneumoniae infection in mice induces chronic lung inflammation, iBALT formation, and fibrosis. PLoS ONE. 2013 Oct 25;8(10):e77447.
Contact the Crother Lab
8700 Beverly Blvd.
Davis Building, Room 4025
Los Angeles, CA 90048