Publications
See a complete PubMed list of publications by Roberta Gottlieb, MD.
Selected Key Publications
- Stastna M, Thomas A, Germano J, Pourpirali S, Van Eyk JE, Gottlieb RA. Dynamic proteomic and miRNA analysis of polysomes from isolated mouse heart after Langendorff perfusion. J Vis Exp. 2018 Aug 29;(138). https://www.jove.com/video/58079/dynamic-proteomic-mirna-analysis-polysomes-from-isolated-mouse-heart.
- Hiraumi Y, Huang C, Andres AM, Xiong Y, Ramil J, Gottlieb RA. Myogenic progenitor cell differentiation is dependent on modulation of mitochondrial biogenesis through autophagy. In: Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, editors. Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet]. Tokyo: Springer; 2016. Chapter 15. https://www.ncbi.nlm.nih.gov/books/NBK500303/.
- Mishra R, Haldar S, Placencio V, Madhav A, Rohena-Rivera K, Agarwal P, Duong F, Angara B, Tripathi M, Liu Z, Gottlieb RA, et al. Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming. J Clin Invest. 2018 Oct 1;128(10):4472-4484. https://www.jci.org/articles/view/99397.
- Elliott EI, Miller AN, Banoth B, Iyer SS, Stotland A, Weiss JP, Gottlieb RA, Sutterwala FS, Cassel SL. Cutting edge: mitochondrial assembly of the NLRP3 inflammasome complex is initiated at priming. J Immunol. 2018 May 1;200(9):3047-3052. http://www.jimmunol.org/content/200/9/3047.
- Coronado M, Fajardo G, Nguyen K, Zhao M, Kooiker K, Jung G, Hu DQ, Reddy S, Sandoval E, Stotland A, Gottlieb RA, Bernstein D. Physiological mitochondrial fragmentation is a normal cardiac adaptation to increased energy demand. Circ Res. 2018 Jan 19;122(2):282-295. https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.117.310725.
- Gottlieb RA, Thomas A. Mitophagy and mitochondrial quality control mechanisms in the heart. Curr Pathobiol Rep. 2017 Jun;5(2):161-169. https://link.springer.com/article/10.1007%2Fs40139-017-0133-y.
- Sin J, McIntyre L, Stotland A, Feuer R, Gottlieb RA. Coxsackievirus B escapes the infected cell in ejected mitophagosomes. J Virol. 2017 Nov 30;91(24). pii: e01347-17. https://jvi.asm.org/content/91/24/e01347-17.
- Kloner RA, Brown DA, Csete M, Dai W, Downey JM, Gottlieb RA, Hale SL, Shi J. New and revisited approaches to preserving the reperfused myocardium. Nat Rev Cardiol. 2017 Nov;14(11):679-693. https://www.nature.com/articles/nrcardio.2017.102.
- Stastna M, Gottlieb RA, Van Eyk JE. Exploring ribosome composition and newly synthesized proteins through proteomics and potential biomedical applications. Expert Rev Proteomics. 2017 Jun;14(6):529-543. https://www.tandfonline.com/doi/full/10.1080/14789450.2017.1333424.
- Taylor D, Gottlieb RA. Parkin-mediated mitophagy is downregulated in browning of white adipose tissue. Obesity (Silver Spring). 2017 Apr;25(4):704-712. https://onlinelibrary.wiley.com/doi/full/10.1002/oby.21786.
- Andres AM, Tucker KC, Thomas A, Taylor DJ, Sengstock D, Jahania SM, Dabir R, Pourpirali S, Brown JA, Westbrook DG, Ballinger SW, Mentzer RM Jr, Gottlieb RA. Mitophagy and mitochondrial biogenesis in atrial tissue of patients undergoing heart surgery with cardiopulmonary bypass. JCI Insight. 2017 Feb 23;2(4):e89303. https://insight.jci.org/articles/view/89303.
- Andres AM, Kooren JA, Parker SJ, Tucker KC, Ravindran N, Ito BR, Huang C, Venkatraman V, Van Eyk JE, Gottlieb RA, Mentzer RM Jr. Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance. Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H219-228. https://www.physiology.org/doi/full/10.1152/ajpheart.00041.2016.
- Stotland A, Gottlieb RA. α-MHC MitoTimer mouse: In vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart. J Mol Cell Cardiol. 2016 Jan;90:53-58. https://www.jmmc-online.com/article/S0022-2828(15)30134-6/fulltext.
- Gottlieb RA, Pourpirali S. Lost in translation: miRNAs and mRNAs in ischemic preconditioning and ischemia/reperfusion injury. J Mol Cell Cardiol. 2016 Jun;95:70-77. https://www.jmmc-online.com/article/S0022-2828(15)30117-6/fulltext.
- Sin J, Andres AM, Taylor DJ, Weston T, Hiraumi Y, Stotland A, Kim BJ, Huang C, Doran KS, Gottlieb RA. Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts. Autophagy. 2016;12(2):369-380. https://www.tandfonline.com/doi/full/10.1080/15548627.2015.1115172.
Contact the Gottlieb Lab
127 S. San Vicente Blvd.
Pavilion, A9100
Los Angeles, CA 90048