Publications
See a complete PubMed list of publications by Kathrin Michelsen, PhD.
Selected Key Publications
- Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Michelsen KS et al. Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut. 2023 Apr 20:gutjnl-2023-329689. doi: 10.1136/gutjnl-2023-329689. Epub ahead of print. PMID: 37080587.
- Shimodaira Y, More SK, Hamade H, Blackwood AY, Abraham JP, Thomas LS, Miller JH, Stamps DT, Castanon SL, Michelsen KS et al. DR3 Regulates Intestinal Epithelial Homeostasis and Regeneration After Intestinal Barrier Injury. Cell Mol Gastroenterol Hepatol. 2023;16(1):83-105. doi: 10.1016/j.jcmgh.2023.03.008. Epub 2023 Apr 1. PMID: 37011811; PMCID: PMC10213104.
- Hamade H, Stamps JT, Stamps DT, More SK, Thomas LS, Blackwood AY, Lahcene NL, Castanon SL, Salumbides BC, Michelsen KS et al. BATF3 Protects Against Metabolic Syndrome and Maintains Intestinal Epithelial Homeostasis. Front Immunol. 2022 Jun 22;13:841065. doi: 10.3389/fimmu.2022.841065. PMID: 35812447; PMCID: PMC9257242.
- Jacob N, Kumagai K, Abraham JP, Shimodaira Y, Ye Y, Luu J, Blackwood AY, Castanon SL, Stamps DT, Michelsen KS, et al. Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo. Sci Rep. 2020 Oct 23;10(1):18189. doi: 10.1038/s41598-020-75168-5. PMID: 33097818; PMCID: PMC7584589.
- Tsuda M, Hamade H, Thomas LS, Salumbides BC, Potdar AA, Wong MH, Nunnelee JS, Stamps JT, Neutzsky-Wulff AV, Barrett RJ, Michelsen KS, et al. A role for BATF3 in TH9 differentiation and T-cell-driven mucosal pathologies. Mucosal Immunol. 2019 May;12(3):644-655. doi: 10.1038/s41385-018-0122-4. Epub 2019 Jan 7. PMID: 30617301; PMCID: PMC6462229.
- Jacob N, Jacobs JP, Kumagai K, Ha CWY, Kanazawa Y, Lagishetty V, Altmayer K, Hamill AM, Von Arx A, Michelsen KS, et al. Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome. Mucosal Immunol. 2018 Sep;11(5):1466-1476. doi: 10.1038/s41385-018-0055-y. Epub 2018 Jul 9. PMID: 29988118; PMCID: PMC6162160.
- Thomas LS, Targan SR, Tsuda M, Yu QT, Salumbides BC, Haritunians T, Mengesha E, McGovern DP, Michelsen KS. The TNF family member TL1A induces IL-22 secretion in committed human Th17 cells via IL-9 induction. J Leukoc Biol. 2017 Mar;101(3):727-737. doi: 10.1189/jlb.3A0316-129R. Epub 2016 Oct 12. PMID: 27733581; PMCID: PMC6608031.
- Lowe EL, Crother TR, Rabizadeh S, Hu B, Wang H, Chen S, Shimada K, Wong MH, Michelsen KS, Arditi M. Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer. PLoS One. 2010 Sep 27;5(9):e13027. doi: 10.1371/journal.pone.0013027. PMID: 20885960; PMCID: PMC2946405.
- Michelsen KS, Thomas LS, Taylor KD, Yu QT, Mei L, Landers CJ, Derkowski C, McGovern DP, Rotter JI, Targan SR. IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein. PLoS One. 2009;4(3):e4719. doi: 10.1371/journal.pone.0004719. Epub 2009 Mar 5. PMID: 19262684; PMCID: PMC2648040.
- Takedatsu H, Michelsen KS, Wei B, Landers CJ, Thomas LS, Dhall D, Braun J, Targan SR. TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation. Gastroenterology. 2008 Aug;135(2):552-67. doi: 10.1053/j.gastro.2008.04.037. Epub 2008 May 7. PMID: 18598698; PMCID: PMC2605110.
Contact the Michelsen Lab
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Davis Research Building, Room 4058
Los Angeles, CA 90048