Publications
See a complete PubMed list of publications by Shuang Chen, MD, PhD.
Selected Key Publications
- Chen S, Markman J, Shimada K, Crother TR, Lane M, Abolhesn A, Shah PK, Arditi M. Sex-specific effects of the Nlrp3 inflammasome on atherogenesis in LDL receptor-deficient mice. JACC Basic Transl Sci. 2020 Jun;5(6):582-598.
- Chen S, Crother TR. MD-2 as a possible therapeutic target for atherosclerosis. EBioMedicine. 2020 May;55:102760.
- Porritt RA, Markman JL, Maruyama D, Kocaturk B, Chen S, Lehman TJA, Lee Y, Fishbein MC, Noval Rivas M, Arditi M. Interleukin-1 beta-mediated sex differences in Kawasaki disease vasculitis development and response to treatment. Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):802-818.
- Nosaka N, Crother TR, Chen S, Arditi M, Shimada K. Optimal tube length of orotracheal intubation for mice. Lab Anim. 2019 Feb;53(1):79-83.
- Noval Rivas M, Wakita D, Franklin MK, Carvalho TT, Abolhesn A, Gomez AC, Fishbein MC, Chen S, Lehman TJ, Sato K, et al. Intestinal permeability and IgA provoke immune vasculitis linked to cardiovascular inflammation. Immunity. 2019 Sep 17;51(3):508-521.e6.
- Tumurkhuu G, Dagvadorj J, Porritt RA, Crother TR, Shimada K, Tarling EJ, Erbay E, Arditi M, Chen S. Chlamydia pneumoniae hijacks a host autoregulatory IL-1β loop to drive foam cell formation and accelerate atherosclerosis. Cell Metab. 2018 Sep 4;28(3):432-448.e4.
- Crother TR, Porritt RA, Dagvadorj J, Tumurkhuu G, Slepenkin AV, Peterson EM, Chen S, Shimada K, Arditi M. Autophagy limits inflammasome during chlamydia pneumoniae infection. Front Immunol. 2019 Apr 12;10:75.
- Chen S, Shimada K, Crother T, Erbay E, Shah PK, Arditi M. Chlamydia and lipids engage a common TLR4/MyD88 innate signaling pathway to promote atherogenesis. J Am Coll Cardiol. 2018 Apr 10;71(14):1553-1570.
- Tumurkhuu G, Shimada K, Dagvadorj J, Crother TR, Zhang W, Luthringer D, Gottlieb RA, Chen S*, Arditi M* (*co-senior author). OGG1-dependent DNA repair regulates NLRP3 inflammasome and prevents atherosclerosis. Circ Res. 2016 Jul 6. pii:CIRCRESAHA.116.308362.
- Wakita D, Kurashima Y, Crother TR, Noval Rivas M, Lee Y, Chen S, Fury W, Bai Y, Wagner S, et al. Role of interleukin-1 signaling in a mouse model of Kawasaki disease-associated abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol. 2016 May;36(5):886-897.
Contact the Chen Lab
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Davis Building, Room D4018
Los Angeles, CA 90048