Won Lab
The Won Lab studies various aspects in biology using computational approaches. We develop computational tools to unravel biological mechanisms and enhance our understanding of biological systems’ integrative data analysis. For this, we apply various machine-learning and artificial intelligence technologies to genome-scale data sets including single cell RNA sequencing and spatial transcriptomics data to understand gene regulation and cell-cell interactions.
We study the function of a cell in harmony with its environment. Besides using classical omics data including epigenomic, proteomic, transcriptomic and genomic data from single as well as bulk cells, we integrate various information such as cell size, neighboring cells and tissue architectures to understand the interaction with the local and the global environment.
Personal Statement
Like human societies, cells live together in a geographically or physically constrained environment. We aim to study cell society using computational as well as molecular approaches.
Kyoung Jae Won, PhD
- Image processing approach combined with spatial transcriptomics
- Cell-contact dependent gene regulation during development, adult-tissue and in disease
- Gene regulatory network reconstruction from data reprocessing
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Won Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Kim J, Rothová MM, Madan E, Rhee S, Weng G, Palma AM, Liao L, David E, Amit I, Won KJ, et al.
Proc Natl Acad Sci USA. 2023 Jan 10;120(2):e2205371120.
Martin PCN, Kim H, Lövkvist C, Hong BW, Won KJ.
Mol Syst Biol. 2022 Sep;18(9):e11080.
Chalabi Hajkarim M, Karjalainen E, Osipovitch M, Dimopoulos K, Gordon SL, Ambri F, Rasmussen KD, Grønbæk K, Helin K, Wennerberg K, Won KJ.
Elife. 2022 Feb 15;11:e73760.
Kim J, T Jakobsen S, Natarajan KN, Won KJ.
Nucleic Acids Res. 2021 Jan 11;49(1):e1.
Contact the Won Lab
700 N. San Vicente Blvd.
Pacific Design Center, Suite G549-C
West Hollywood, CA 90069