Crother Lab
Areas of research in the Crother Laboratory include acute lung infections and host-pathogen interactions, in addition to allergic asthma models. The Crother Lab also investigates the mechanisms by which RIP2 in T cells controls the induction of pathogenic Th17 skewing and its implication in inflammatory bowel disease mouse models. Finally, we are studying how C. pneumoniae infections can modulate Alzheimer’s disease progression.
The Crother Laboratory is affiliated with the Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences and the Pediatrics Department.
Personal Statement
As a researcher, one of my key interests has centered on host-pathogen interactions. This has led me to investigate how Borrelia burgdorferi, the causative agent of Lyme Disease, remakes itself when it infects a mammalian host, and how Chlamydia pneumoniae infections can drive asthmatic responses, and also exacerbate atherosclerotic plaque development. More recently, I have become interested in the possibility that infectious agents may play a role in the development and progression of Alzheimer’s Disease. While there is evidence that infections may play a role in AD, few direct studies have been attempted, highlighting the need for new investigations.
Timothy R. Crother, PhD
- The Role of Infectious Diseases in the Etiology of Alzheimer’s Disease
- T-cell RIP2 and Inflammatory Bowel Disease
- Pulmonary Infections
- Innate Immunity and Asthma
Meet Our Team
Learn more about the researchers of the Crother Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Publications
Learn more about the recent research publications from the Crother Lab.
Contact the Crother Lab
8700 Beverly Blvd.
Davis Building, Room 4025
Los Angeles, CA 90048