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Research Areas

The Di Vizio Laboratory investigates the molecular mechanisms of tumor progression to advanced disease in prostate and lung cancers, in addition to other human tumors, with a significant focus on intercellular communication between tumor and stromal cells.

Specific areas of study include:
  • The role of large oncosomes in intercellular communication and in tumor growth and metastasis in solid tumors
  • Molecular profiling of large oncosomes and other cancer-derived EVs by next generation sequencing and proteomics
  • Molecular mechanisms and functional consequences of the internalization of large oncosomes in recipient cells
  • Functional characterization of large oncosome-encapsulated mitochondria
  • Identification of biomarkers using liquid biopsy

Contact the Di Vizio Lab

110 N George Burns Rd.,
Davis Building, Room 5094A
Los Angeles, CA 90048