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Research Areas

The pituitary regulates major physiological functions, including growth, sexual maturation and metabolism, and influences gene expression and epigenetic state in other tissues. We are using single-cell multi-omics approaches to elucidate the cellular heterogeneity, regulatory networks and pathophysiological changes in the pituitary.

Ongoing Research


  • Characterization of the epigenetic mechanisms underlying pituitary adenomas
  • FSHB regulation in pituitary gonadotropes
  • Mechanisms underlying gene circuit regulation during the estrous cycle
  • Pituitary plasticity during hypothyroidism

Contact the Ruf-Zamojski Lab

8700 Beverly Blvd.
Davis Building, Room 5025
Los Angeles, CA 90048