Publications
See a complete PubMed list of publications by Hisashi Tanaka, MD, PhD.
Selected Key Publications
- Watanabe T, Marotta M, Suzuki R, Diede SJ, Tapscott SJ, Niida A, Chen X, Mouakkad L, Kondratova A, Giuliano AE, Orsulic S, Tanaka H. Impediment of replication forks by long non-coding RNA provokes chromosomal rearrangements by error-prone restart. Cell Rep. 2017 Nov 21;21(8):2223-2235. http://www.cell.com/cell-reports/fulltext/S2211-1247(17)31583-8.
- Marotta M, Onodera T, Johnson J, Budd GT, Watanabe T, Cui X, Giuliano AE, Niida A, Tanaka, H. Palindromic amplification of ERBB2 oncogene in HER2-positive breast cancer. Sci Rep. 2017 Feb 17;7:41921. http://www.nature.com/articles/srep41921.
- Kondratova A, Watanabe T, Marotta M, Cannon M, Segall AM, Serre D, Tanaka H. Replication fork integrity and intra-S phase checkpoint suppress gene amplification. Nucleic Acids Res. 2015 Mar 11;43(5):2678–2690. https://academic.oup.com/nar/article/43/5/2678/2453179.
- Marotta M, Chen X, Watanabe T, Faber PW, Diede SJ, Tapscott S, Tubbs R, Kondratova A, Stephens R, Tanaka H. Homology-mediated end-capping as a primary step of sister chromatid fusion in the breakage-fusion-bridge cycles. Nucleic Acids Res. 2013 Nov;41(21):9732-9740. https://academic.oup.com/nar/article/41/21/9732/1277663.
- Marotta M, Chen X, Inoshita A, Stephens R, Budd GT, Crowe JP, Lyons J, Kondratova A, Tubbs R, Tanaka H. A common copy-number breakpoint of ERBB2 amplification in breast cancer colocalizes with a complex block of segmental duplications. Breast Cancer Res. 2012 Nov 26;14(6):R150. https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr3362.
- Tanaka H, Yao MC. Palindromic gene amplification—an evolutionarily conserved role for DNA inverted repeats in the genome. Nat Rev Cancer. 2009 Mar;9(3):216-224. http://www.nature.com/articles/nrc2591.
- Zhao Y, Marotta M, Eichler EE, Eng C, Tanaka H. Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes. PLOS Genet. 2009 May;5(5):e1000472. http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1000472.
- Tanaka H, Bergstrom DA, Yao MC, Tapscott SJ. Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification. Nat Genet. 2005 Mar;37(3):320-327. https://www.nature.com/articles/ng1515.
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