Publications
Research
Research is considered an important aspect of education and has strong departmental and institutional support, including a large, well-organized biobank. Participation in at least one research project over the four-year program is required, typically resulting in an abstract and publication. Most residents undertake several studies. Residents select their projects and the faculty with whom they want to work, with clinical and/or translational studies available in all anatomic pathology and clinical pathology subspecialty areas.
2017-19 House Staff Publications
- Hunt B, Sacks W. Thyroid tumor board: the pathologic criteria of poorly differentiated thyroid cancer can be difficult to distinguish from differentiated thyroid carcinoma. Clin Thyroidol. 2017 Jun;29(6):244-246.
- Chang C, Zhao Q, Kim J, Alzahrani K, Del Re D, Fraidenraich D. Hematopoietic Id deletion triggers endomyocardial fibrotic and vascular defects in the adult heart. Sci Rep. 2017 Jun 8;7(1):3079.
- Serapio P, Frye J, Mehrpoo N. Difficulty swallowing, sore throat, cough. Cedars-Sinai Department of Radiology Case of the Month. 2017 Nov.
- Siref A, Huang Q. Chewing the bone: bone marrow with adult T-cell leukemia/lymphoma. Blood. 2018 Feb 22;131(8):940.
- Hunt B, Chi Z, Huang Q. Extracavitary primary effusion lymphoma. Cedars-Sinai Department of Pathology and Laboratory Medicine Case of the Month. 2018 Apr.
- Siref A, Patel V, Reith JD, Balzer BL, Shon W. Evaluation of p16 protein expression and CDKN2A deletion in conventional and fibrosarcomatous dermatofibrosarcoma protuberans. Pathology. 2018 Jun;50(4):474-475.
- Wield A, Hodeib M, Khan MS, Gubernick L, Li A, Kandukuri S. Sebaceous carcinoma arising within an ovarian mature cystic teratoma: a case report with discussion of clinical management and genetic evaluation. Gynecol Oncol Rep. 2018 Aug 29;26:37-40.
- Guzman S, Kitahara S. Spindle cell lesion in the bone marrow. Blood. 2018 Sep 6;132(10):1085.
- Frye J, Dhall D. A peculiar case of diarrhea. Cedars-Sinai Department of Pathology Case of the Month. 2018 Sep.
- Watson R, Frye J, Trieu M, Yang MX. Primary undifferentiated pleomorphic cardiac sarcoma with MDM2 amplification presenting as acute left-sided heart failure. BMJ Case Rep. 2018 Sep 30;2018. Pii:bcr-2018-226073.
- Hunt B, Bannykh S, Moser F. Intra-arterial spread of Mucormycetes mediates early ischemic necrosis of brain and suggests new venues for prophylatic therapy. Neuropathology. 2018 Oct;38(5):539-541.
- Wong M, Frye J, Kim S, Marchevsky AM. The use of screencasts with embedded whole-slide scans and other hyperlinks to teach anatomic pathology in a supervised digital environment. J Pathol Inform. 2018 Nov 14;9:39.
- Vail E, Song J, Xu J, Frye JS, Pao A, Aguiluz A, Zhang W, Alkan S, Berz D, Engman D, Lopategui J. The NGS solid tumor panel gene count “Arms Race”: why bigger isn't always better. J Mol Diagn. 2018 Nov;20(6):1040-1056.
- Siref A, Hendifar A, Balzer B. Primary visceral merkel cell carcinoma: a case report and review of the literature. Am J Dermatopathol. 2018 Dec;40(12):927-929.
- Dong E, Morris K, Sodhi G, Chang D, Czer L, Chung J, Zabner R, Raastad K, Klapper E, Kobashigawa J, Nurok M. Neuroinvasive West Nile virus post-heart transplantation: a case report. Transplant Proc. 2018 Dec;50(10):4057-4061.
- Share M, Giannini G, Kim S, Singh S. Intravascular B-cell lymphoma: case report of a rare cause of pulmonary arterial hypertension. Eur Heart J Case Rep. 2019 Feb 2;3(1):yty150.
- Walts AE, Frye J, Engman DM, Marchevsky AM. Carcinoid tumors of the thymus and Cushing’s syndrome: clinicopathologic features and current best evidence regarding the cell of origin of these unusual neoplasms. Ann Diagn Pathol. 2019 Feb;38:71-79.
- Lam R, Hunt B, Arreola-Owen O. Abdominal wall schwannoma. Fed Pract. 2019 Mar;36(3):129-133.
- Siref AB, Huynh CAT, Balzer BL, Frishberg DP, Essner R, Shon W. Diagnostic utility of dual 5-hmC/Melan-A immunohistochemistry in differentiating nodal nevus from metastatic melanoma: an effective first-line test for the work-up of sentinel lymph node specimen. J Cutan Pathol. 2019 Apr;46(4):261-266.
- Wong M, Larson BK, Dhall D. Neuroendocrine proliferations in inflammatory bowel disease: differentiating neuroendocrine tumors from neuroendocrine cell micronests. Histopathology. 2019 Feb;74(3):415-423.
- Gertych A, Swiderska-Chadaj Z, Ma Z, Ing N, Markiewicz T, Cierniak S, Salemi H, Guzman S, Walts AE, Knudsen BS. Convolutional neural networks can accurately distinguish four histologic growth patterns of lung adenocarcinoma in digital slides. Sci Rep. 2019 Feb 6;9(1):1483.
- Sarmiento J, Medina O, Do AS, Farber S, Chu RM. Resection of cervical juxtacortical chondroma and circumferential spinal stabilization for kyphotic deformity. Cureus. 2019 Apr 22;11(4):e4523.
- Yagi S, Arcega R, Ho AS, Balzer B. Unusual presentation of primary syphilis as retropharyngeal chancre: a case report. OTO Open. 2019 Apr;3(2).
House Staff Abstracts and Presentations
USCAP 2019
Title: Diagnostic Utility of 5hmC Immunohistochemistry in Differentiating Seminoma from Nonseminomatous Elements: A Study of 83 Testicular Germ Cell Tumors
Authors: Makhoul E, Siref A, Cox B, Luthringer D, De-Peralta Venturina M
Title: Diagnostic Utility of 5hmC in Distinguishing Hepatocellular Neoplasia from Non-Neoplastic Liver
Authors: Siref A, Larson B, Guindi M
Title: 5-hmC as a Potential Biomarker in Urothelial Neoplasia
Authors: Siref A, Cox B, De Peralta-Venturina M, Luthringer D
Title: An Assessment of the Heterogeneous Expression of Glypican-3 (GPC3) in Hepatocellular Carcinoma (HCC) in the Era of GPC3 as a Biomarker
Authors: Cox B, Waters K, Dhall D, Larson B, Guindi M
Title: Diagnostic Utility of 5hmC Immunohistochemistry in Differentiating Seminoma from Nonseminomatous Elements: A Study of 83 Testicular Germ Cell Tumors
Authors: Makhoul E, Siref A, Cox B, Luthringer D, De-Peralta Venturina M
Title: Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in Cutaneous Squamous Cell Carcinoma of Organ Transplant Recipients
Authors: Shon W, Khan M, Cox B, Balzer B
Improved Recognition of Hematogones from Precursor B-cell Acute Lymphoblastic Leukemia by a Single Tube Flow Cytometric Analysis
Authors: Don M, Lim W, Cox B, Huang Q, Kitahara S, Lopategui J, Alkan S
Title: Chromosomal Microarray Identifies Distinctive Genomic Signatures in Uterine Smooth Muscle Tumors of Uncertain Malignant Potential (STUMP), Leiomyosarcoma, and Leiomyoma with Bizarre Nuclei
Authors: Khullar G, Medeiros F, Balzer B, Silberman A, Baden K, Halprin C, Khullar R, Khan M, Vail E, Schreck R, Song J, Alkan S, Engman D, Lopategui J
Title: Novel Immunohistochemical Panel Utilizes DNA Methylation Markers 5HMC and H327Kme3 to Characterize Uterine Smooth Muscle Tumors
Authors: Halprin C, Khullar G, Alkan S, Lopategui J, Balzer B, Medeiros F
Title: The Use of Kaplan-Meier Statistics and Neural Networks to Estimate Prognosis in Patients with Pulmonary Typical Carcinoid Tumors
Authors: Marchevsky A, Manzoor D, Walts A
Title: Evaluation for Serrated Epithelial Changes (SEC) in Prior Biopsies of Patients with Inflammatory Bowel Disease (IBD) Associated Flat Dysplasia
Authors: Makhoul E, Chi Z, Dhall D, Waters K
Title: Next Generation Sequencing Identifies Mutational Distinction between Primary and Metastatic Colorectal Carcinoma: Implications for Specimen and Therapy Selection
Authors: Khullar G, Vail E, Frye J, Makhoul E, Martinez JS, Engman D, Lopategui J
Title: Inflammatory Bowel Disease (IBD) - Associated Dysplasia Shows an Increased Mutational Load In Comparison to Sporadic Adenomas in Patients With IBD
Authors: Taguibao RA, Vail E, Makhoul E, Khullar G, Guindi M, Waters, Lopategui, Dhall D
Title: INSM1 Immunohistochemical Evaluation of Merkel Cell Carcinoma and Other Cutaneous Epithelial Tumors
Authors: Frye J, Mertens R, Frishberg D, Balzer B, Shon W
Title: Interobserver Agreement and the Utility of Immunohistochemistry (IHC) for Assessing Tumor Budding in Colorectal Adenocarcinoma
Authors: Wong M, Guindi M, Chi Z, Dhall D, Kim S, Larson B, Mertens R, Taguibao RA, Waters K
Title: Autoimmune Metaplastic Atrophic Gastritis (AMAG): Assessment of Correlation with Serology and Adequacy of Clinical Follow-Up
Authors: Imam S, Wong M, Dhall D, Waters K
Title: Chromosomal Microarray Identifies Imbalances in Oncogenes and Tumor Suppressor Genes Predictive of Early vs Late Relapse in EGFR Mutated Non-Small Cell Lung Cancer
Authors: Khullar G, Baden K, Khan M, Khullar R, Vail E, Schreck R, Song J, Marchevsky A, Engman D, Lopategui J
Other Presentations
Oral platform presentation: Khan MS, Frishberg D. Dermatopathology Trainee World Cup. A case report of an acquired medallion-like dermal dendrocyte hamartoma presenting as a dermal nodule on the left shin. International Society of Dermatopathology Meeting; Feb. 14, 2018. San Diego, California.
2017-19 Awards and Honors
Andrew Siref, MD
- 2017 Second Place: Resident and Fellow Symposium, Los Angeles Society of Pathologists
- 2018 Pathology and Laboratory Medicine Academic Pathology Mini Grant Award for Basic, Translational and Clinical Research, Cedars-Sinai
Brian Cox, MD
- December 2018 Just Say Know! From Mentoring to High Performance USCAP/ASCP Leadership Symposium, Palm Springs, California
Chelsea Halprin, MD
- 2018 Mini Grant Recipient, Cedars-Sinai Department of Pathology and Laboratory Medicine
Corey Chang, MD, PhD
- 2018 Travel Award, California Society of Pathologist, Sacramento, California
- Joseph Frye, MD
- 2017 Nathan B. Friedman Research Travel Award, Cedars-Sinai
- 2017-18 Co-Investigator: Corticotropin Releasing Hormone Expression in Normal Thymus and Thymic Neuroendocrine Neoplasms. Mini-grant approval funded through the Department of Pathology and Laboratory Medicine, Cedars-Sinai. Principal investigator: Alberto Marchevsky, MD
- 2017-18 Co-Investigator: INSM1 is a Novel Immunohistochemical Marker for Neuroendocrine Tumors. Mini-grant approval and funding provided through the Department of Pathology and Laboratory Medicine, Cedars-Sinai. Principal investigator: Wonwoo Shon, MD
Mary Wong, MD
- 2017 Finalist: Nathan B. Friedman Award in Research, Department of Pathology, Cedars-Sinai
- 2018 First Place: Los Angeles Society of Pathologists Resident/Fellow Symposium, Los Angeles, California
- 2018 Leo G. Rigler Award for Academic Achievement, Department of Pathology, Cedars-Sinai
- 2018 Nathan B. Friedman Prize for Excellence in Research, Department of Pathology, Cedars-Sinai
Have Questions or Need Help?
If you have questions or would like to learn more about the Anatomic and Clinical Pathology Residency Program at Cedars-Sinai, please call or send a message to Program Coordinator, Chau Nguyen.
Department of Pathology and Laboratory Medicine
8700 Beverly Blvd., Room 8709
Los Angeles, CA 90048-1804