Ainsworth Lab

The primary focus of our lab is the development of integrative systems biology methods for multi-omics data. We have specific interests in transcriptional dysregulation and aberrant signaling in autoimmune disorders, such as Rheumatoid Arthritis, Scleroderma, and Lupus, and we are working to gain new insights into disease mechanisms. With strong connections to clinical scientists, we prioritize the application of interpretable methods that can translate to verifiable predictions in vitro or in vivo. Further research themes leverage our lab’s unique access to autoimmune patient data with comprehensive clinical annotation and include the use of machine learning methods to uncover complex patterns of disease association thus developing new prognostic and patient stratification strategies.