Publications
See a complete PubMed list of publications by Ebru Erbay, MD, PhD.
Selected Key Publications
- Ona UI, Yildirim AD, Tufanli O, Cimen I, Kocaturk B, Hamid SM, Chen S, Sin J, Shimada K, Shah PK, Gottlieb RA, Arditi M, Erbay E. Intercepting the lipid-induced integrated stress response reduces atherosclerosis. J Am Coll Cardiol. 2019 Mar 19;73(10):1149-1169.
- Tufanli O, Telkoparan-Akillilar P, Acosta-Alvear D, Kocaturk B, Cimen I, Onat UI, Hamid SM, Walter P, Weber C, Erbay E. Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proc Natl Acad Sci USA. 2017 Feb 21;114(8):E1395-E1404.
- Çimen I, Kocatürk B, Koyuncu S, Apaydın O, Tufanlı Ö, Onat UI, Demirsoy Ş, Aykut GZ, Nguyen UT, Watkins SM, Hotamışlıgil GS, Erbay E. Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and Inflammasome activation. Sci Transl Med. 2016 Sep 28;8(358):358ra126.
- Erbay E, Babev VR, Mayers JR, Makowski L, Tape KN, Fazio S, Wiest MM, Watkins SM, Linton MF, Hotamisligil GS. Reducing ER stress through a macrophage lipid chaperone alleviates atherosclerosis. Nat Med. 2009 Dec;15(12):1383-1391.
- Cimen I, Yildirim Z, Dogan AE, Yildirim AD, Tufanli O, Onat UI, Nguyen U, Watkins SM, Weber C, Erbay E. Double bond configuration of palmitoleate is critical for atheroprotection. Mol Metab. 2019 Oct;28:58-72. doi: 10.1016/j.molmet.2019.08.004. Epub 2019 Aug 7.
- Tumurkhuu G, Dagvadorj J, Porritt RA, Crother TR, Shimada K, Tarling EJ, Erbay E, Arditi M, Chen S. Chlamydia pneumoniae hijacks a host autoregulatory IL-1β loop to drive foam cell formation and accelerate atherosclerosis. Cell Metab. 2018 Sep 4;28(3):432-448.e4.
- Koelwyn GJ, Corr EM, Erbay E, Moore KJ. Regulation of macrophage immunometabolism in atherosclerosis. Nat Immunol. 2018 Jun;19(6):526-537. doi: 10.1038/s41590-018-0113-3. Epub 2018 May 18.
- Chen S, Shimada K, Crother TR, Erbay E, Shah PK, Arditi M. Chlamydia and lipids engage a common signaling pathway that promotes atherogenesis. J Am Coll Cardiol. 2018 Apr 10;71(14):1553-1570. doi: 10.1016/j.jacc.2018.01.072.
- Babaev VR, Yeung M, Erbay E, Ding L, Zhang Y, May JM, Fazio S, Hotamisligil GS, Linton MF. Jnk1 deficiency in hematopoietic cells suppresses macrophage apoptosis and increases atherosclerosis in low-density lipoprotein receptor null mice. Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1122-1131.
- Babaev VR, Runner RP, Fan D, Ding L, Zhang Y, Tao H, Erbay E, Görgün CZ, Fazio S, Hotamisligil GS, Linton MF. Macrophage Mal1 deficiency suppresses atherosclerosis in low-density lipoprotein receptor-null mice by activating peroxisome proliferator-activated receptor-γ-regulated genes. Arterioscler Thromb Vasc Biol. 2011 Jun;31(6):1283-1290.
Contact the Erbay Lab
If you have any questions or would like more information about the research work at the Erbay Laboratory, please give us a call.
Advanced Health Sciences Pavilion, Room A9104
127 S. San Vicente Blvd.
Los Angeles, CA 90048